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Physician training · MRCP(UK) Part 1

MRCP Part 1.Know the medicine. Pass the paper.

  • Know exactly what to revise. Your tracker finds your weakest specialties and picks the next one.
  • Every answer explained, with the guideline or textbook chapter behind it, so you only read what you got wrong.
  • Clinical sciences included: immunology, genetics, physiology and statistics, the questions most banks skimp on.
  • Two timed mock exams of 100 questions in 3 hours, the length of one real paper.

Pay once through Lemon Squeezy. No subscription, no auto-renewal.

Next sitting: Wed 20 Jan 2027 · 11 weeks to go

MRCP Part 1Question & explanation

Arrhythmias: atrial fibrillation

A 63-year-old man is found to have persistent atrial fibrillation at a routine review. He has treated hypertension but no diabetes, heart failure, vascular disease or previous stroke. Echocardiography shows a structurally normal heart. His ORBIT bleeding score indicates low bleeding risk. Which is the most appropriate approach to stroke prevention?

A
Offer aspirin 75 mg daily as the sole antithrombotic agent
B
Advise that no stroke prevention therapy is indicated at his risk level
C
Consider a direct-acting oral anticoagulant · Correct
D
Offer warfarin as the preferred first-line anticoagulant
E
Refer for left atrial appendage occlusion in preference to drugs
Understand why.

His CHA2DS2-VASc score is 1 (hypertension only; age under 65; male). NICE NG196 says to consider a direct-acting oral anticoagulant (DOAC) for men with a score of 1, taking bleeding risk into account (1.6.4), and to offer one when the score is 2 or more (1.6.3).

NICE NG196 Atrial fibrillation — 1.2.1, 1.6.3, 1.6.4 and 1.6.7
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Everything in your MRCP Part 1 pass.

Every pass length has the same features. Choose the time you need, not the features you can afford.

  • No past papers? Questions across every MRCP(UK) Part 1 blueprint specialty, and two timed 100-question mock exams in the exam format
  • Too much to read? The NICE or specialty guideline, or textbook section, behind every answer, so you only read what you got wrong
  • Don’t know what’s next? A tracker that picks your next topic, made for 20-minute sessions on your phone
  • Forgetting what you learnt? Wrong answers come back after 10 minutes, then after 1, 3 and 7 days
  • How do you fit it all in? A week-by-week study plan to your sitting, rebuilt from your answers
  • Will it renew? No. One payment, no subscription

Your pass starts as soon as you pay. By paying, you ask for access to start now and accept that you lose your 14-day right to cancel once you start using the question bank. Cancellations and refunds.

Find your pace.
Test your understanding.

Switch from learning by specialty to a timed mock exam. No feedback until you submit, then your score by specialty, every explanation and what to read first.

Each mock exam is one 100-question, 3-hour paper on the blueprint; the two together make a full 200-question Part 1. Mock exams need an active pass. For official exam rules and dates, check MRCP(UK).

Your syllabus
coverage.

Every specialty on the MRCP(UK) Part 1 blueprint, plus clinical sciences and statistics. Explore what each covers and the sources behind it.

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18 topic sections

Cardiology

Arrhythmias: atrial fibrillation · Arrhythmias: pre-excitation · Arrhythmias: narrow-complex tachycardia · Arrhythmias: broad-complex tachycardia · Arrhythmias: long QT and torsades de pointes · Arrhythmias: inherited channelopathies · and more

Sources: NICE NG196 Atrial fibrillation; Kumar and Clark Clinical Medicine; RCUK Adult bradyarrhythmia algorithm 2025; NICE NG185 Acute coronary syndromes; and others

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Clinical pharmacology and therapeutics

Pharmacokinetics: elimination kinetics · Pharmacokinetics: steady state · Pharmacokinetics: volume of distribution · Pharmacogenetics: CYP2D6 · Pharmacogenetics: thiopurines · Pharmacogenetics: HLA associations · and more

Sources: Medical Sciences Naish; Kumar and Clark Clinical Medicine; MHRA Drug Safety Update January 2024; MHRA Drug Safety Update June 2024; and others

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Clinical sciences: cell biology, anatomy, biochemistry, physiology, genetics and immunology

Genetics: anticipation · Genetics: trinucleotide repeat disorders · Genetics: types of point mutation · Genetics: frameshift mutations · Genetics: genomic imprinting · Genetics: mitochondrial inheritance · and more

Sources: Medical Sciences Naish; Kumar and Clark Clinical Medicine

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Statistics, epidemiology and evidence-based medicine

Diagnostic test evaluation: sensitivity · Diagnostic test evaluation: specificity · Diagnostic test evaluation: positive predictive value · Diagnostic test evaluation: predictive values and prevalence · Diagnostic test evaluation: likelihood ratio · Risk measures: relative risk · and more

Sources: Medical Statistics Made Easy

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Dermatology

Psoriasis: clinical variants · Psoriasis: exacerbating drugs · Psoriasis: topical treatment · Psoriasis: topical corticosteroid safety · Psoriasis: scalp disease · Acne vulgaris: isotretinoin · and more

Sources: Kumar and Clark Clinical Medicine; NICE CG153 Psoriasis; NICE CG57 Atopic eczema in under-12s; NICE NG14 Melanoma; and others

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Endocrinology, diabetes and metabolic medicine

Thyroid: hypothyroidism · Thyroid: Hashimoto's thyroiditis · Thyroid: Graves' disease · Thyroid: antithyroid drug toxicity · Thyroid: radioactive iodine · Adrenal: Cushing's syndrome · and more

Sources: NICE NG145 Thyroid disease; Kumar and Clark Clinical Medicine; NICE NG243 Adrenal insufficiency; NICE NG28 Type 2 diabetes in adults; and others

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Gastroenterology and hepatology

Dyspepsia: H. pylori test and treat · Dyspepsia: H. pylori testing method · Peptic ulcer: H. pylori eradication · Peptic ulcer: NSAID-associated ulcer · Upper GI bleeding: risk assessment · Upper GI bleeding: timing of endoscopy · and more

Sources: NICE CG184 Gastro-oesophageal reflux disease and dyspepsia; NICE CG141 Acute upper gastrointestinal bleeding; Kumar and Clark Clinical Medicine; NICE NG12 Suspected cancer: recognition and referral; and others

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Geriatric medicine

Delirium: risk factors · Delirium: initial management · Delirium: pharmacological treatment of distress · Delirium: hypoactive presentation · Falls: multifactorial assessment · Falls: orthostatic hypotension · and more

Sources: NICE CG103 Delirium; NICE NG249 Falls; NICE CG124 Hip fracture; NICE NG97 Dementia; and others

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Haematology

Iron deficiency: diagnosis · Iron deficiency: oral treatment · Iron deficiency: parenteral iron · Anaemia of chronic disease · Thalassaemia trait · Vitamin B12 deficiency: who to test · and more

Sources: Kumar and Clark Clinical Medicine; NICE NG239 Vitamin B12 deficiency; NICE NG24 Blood transfusion; NICE NG52 Non-Hodgkin lymphoma; and others

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Infectious diseases

Viral infections: varicella zoster · Viral infections: Epstein–Barr virus · Viral infections: cytomegalovirus · Viral infections: mumps · Viral infections: measles · Viral infections: parvovirus B19 · and more

Sources: Kumar and Clark Clinical Medicine; NICE NG240 Bacterial meningitis and meningococcal disease; NICE NG95 Lyme disease; UKHSA Green Book Chapter 30 Tetanus; and others

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Neurology

Localisation: language disorders · Localisation: visual pathways · Neuro-ophthalmology: optic neuritis · Neuro-ophthalmology: pupils · Neuro-ophthalmology: eye movements · Neuro-ophthalmology: cranial nerve palsies · and more

Sources: Kumar and Clark Clinical Medicine; NICE CG150 Headaches in over 12s; NICE NG217 Epilepsies in children, young people and adults; NICE NG71 Parkinson's disease in adults; and others

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Oncology

Oncological emergencies: neutropenic sepsis · Oncological emergencies: spinal cord compression · Oncological emergencies: superior vena cava obstruction · Oncological emergencies: hypercalcaemia · Oncological emergencies: tumour lysis syndrome · Immunotherapy: adverse effects · and more

Sources: Kumar and Clark Clinical Medicine; NICE NG234 Spinal metastases and metastatic spinal cord compression; NICE NG12 Suspected cancer: recognition and referral

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Medical ophthalmology

Red eye: acute angle-closure glaucoma · Glaucoma: primary open-angle · Uveitis · Retinal vascular occlusion · Retinal detachment · Age-related macular degeneration · and more

Sources: Kumar and Clark Clinical Medicine

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Palliative medicine and end of life care

Pain: starting strong opioids · Pain: opioid titration · Pain: opioids in renal impairment · Pain: opioid toxicity · Pain: transdermal opioids · Nausea and vomiting · and more

Sources: NICE CG140 Palliative care for adults: strong opioids for pain relief; Kumar and Clark Clinical Medicine; NICE CG140 Palliative care for adults: strong opioids

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Psychiatry

Neuroleptic malignant syndrome · Serotonin syndrome · Lithium toxicity · Lithium monitoring · Lithium adverse effects · Lithium: stopping treatment · and more

Sources: Kumar and Clark Clinical Medicine; Oxford Handbook of Psychiatry; NICE CG185 Bipolar disorder; NICE CG178 Psychosis and schizophrenia in adults; and others

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Renal medicine

Renal physiology: tubular transport · Renal physiology: tubuloglomerular feedback · Assessment of kidney function · Urinalysis · Nephrotic syndrome: minimal change disease · Nephrotic syndrome: membranous nephropathy · and more

Sources: Kumar and Clark Clinical Medicine; NICE NG203 Chronic kidney disease; NICE NG118 Renal and ureteric stones; NICE NG148 Acute kidney injury

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Respiratory medicine

Lung function: flow–volume loops · Lung function: gas transfer · Lung function: lung volumes · Respiratory physiology: control of ventilation · Respiratory physiology: diaphragm · Asthma: diagnosis · and more

Sources: Kumar and Clark Clinical Medicine; NICE NG245 Asthma (BTS/NICE/SIGN); NICE NG115 COPD in over 16s; NICE NG250 Pneumonia; and others

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Rheumatology

Rheumatoid arthritis: referral · Rheumatoid arthritis: serology · Rheumatoid arthritis: first-line DMARD · Rheumatoid arthritis: palindromic disease · Rheumatoid arthritis: treat-to-target · Rheumatoid arthritis: disease activity · and more

Sources: NICE NG100 Rheumatoid arthritis in adults; Kumar and Clark Clinical Medicine; NICE NG226 Osteoarthritis in over 16s; NICE NG219 Gout; and others

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Exam at a glance

What is the MRCP Part 1 exam?

MRCP(UK) Part 1 is the first written exam of the Membership of the Royal Colleges of Physicians, the entry exam for UK physician training. It is two papers of 100 best-of-five questions, each 3 hours, testing core clinical medicine and the clinical sciences behind it.

Last checked 25 October 2026 against the MRCP(UK) Part 1 format and blueprint. MedMocks is independent of MRCP(UK), so always confirm details there.

MRCP Part 1: key facts
Run byMRCP(UK), for the Federation of the Royal Colleges of Physicians
FormatTwo papers of 100 best-of-five questions, no negative marking
Time3 hours per paper, on computer at a test centre
What it testsCore clinical medicine across 17 specialties, plus clinical sciences (25 of 200 questions)
SittingsUsually January and September. Next sitting: Wed 20 Jan 2027 (MRCP(UK); always confirm with them.)
MedMocks bankExplained, sourced questions across every blueprint specialty and two timed mock exams

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Clear answers.

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What does the MRCP Part 1 pass include?

Your MRCP Part 1 pass covers the full MRCP Part 1 question bank and two timed 100-question mock exams, every answer explained with its source; a tracker that picks your next topic, with smart revision and a readiness score; and a week-by-week study plan to your sitting. Paid once, with no subscription and no automatic renewal.

Can I try it before paying?

Yes. Try five questions with worked explanations and their sources, with no account or card. Then create a free account for the mini mock exam: 20 timed questions across the specialties, then your weakest topics and what to read.

Where do the answers come from?

Every question is written for MedMocks from Kumar and Clark, Medical Sciences, the Oxford Handbook of Clinical Medicine, NICE guidelines and the UK specialty societies (ESC, BTS, BSG, BSR, BSH, BAD), the UKHSA Green Book and MHRA Drug Safety Updates. Each explanation names the source and section, so you can read it.

How does the tracker know what I should revise?

After each session, your tracker shows the topics you’re scoring below 60% and the exact source to read. Questions you get wrong come back after 10 minutes, then after 1, 3 and 7 days. Your readiness score appears after 50 questions across 3 topics. It is a study guide, not a prediction of your result.

Will I be charged again?

No. A pass is a single payment through Lemon Squeezy, our merchant of record. There is no subscription and no automatic renewal.

Does it work on my phone?

Yes. MedMocks runs in your phone’s browser, so a 20-minute session between jobs counts. Your progress is saved to your account.

Is MedMocks an official MRCP(UK) resource?

No. MedMocks is independent revision material and is not affiliated with or endorsed by MRCP(UK) or the Federation of the Royal Colleges of Physicians. The questions are original, not past exam questions. Check the MRCP(UK) website for the official rules and dates.

What is the format of MRCP Part 1?

Two papers of 100 best-of-five multiple choice questions, 3 hours each, taken on computer. Each question has one correct answer and four plausible distractors, with no negative marking. The blueprint covers 17 specialties plus clinical sciences: about 14 questions each in cardiology, endocrinology, gastroenterology, infection, neurology, renal, respiratory and rheumatology, 15 in clinical pharmacology and 25 in clinical sciences.